In a best case scenario, you will be able to find a high quality pre-appraised information source to answer your question.
However, those are not available for all topics. Furthermore, you may also find it useful to appraise pre-appraised information. You should always question the quality of the material you find. Remember, a poorly done systematic review is not better than a well done randomized controlled trial. On this page, you will find some resources to help you with appraising the material you find.
Additional Users’ Guides Published After the Original Series