Some databases allow you to search for information on consumers based on MSA or DMA.
MSA: Metropolitan Statistical Area. The US government divides the country into MSAs which usually include a metropolitan city and the suburban areas surrounding.
DMA: Designated Market Area. This is a geographic region set up by the Nielsen Company (ratings). Each DMA is made up of the counties that make up a city's television viewing area. Note: Indianapolis's DMA ranking for 2019 is 28.
How to create a demographic profile
(This example shows someone who makes business purchase decisions but you can also create profiles on folks who have certain medical conditions, use certain pharmaceuticals, and have different health attitudes.)
How to create at crosstab
How to interpret indices in MRI Simmons
Note: These are all web resources.